a woman with skin condition that may qualify for a vitiligo research study

Vitiligo Research Study

A Vitiligo Research Study for Skin Color Restoration
Benefits of Joining a Clinical Trial
  • Study-related health assessments to see if you and the study are a good fit.
  • Continuous monitoring of your health by the study clinic team.
  • Access to an investigational medicine that is not approved for use by the public.
  • The study length has been designed to allow enough time to see whether the investigational medicine could help restore the skin's natural color in people living with vitiligo.
Gender
Male and Female
Ages
18+
Status
Coming Soon
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Overview

Vitiligo Research Study

A clinical study to see if an investigational medicine could help restore the skin's natural color.

Vitiligo happens when your body's immune system mistakenly attacks the cells that give your skin its color, causing lighter or white patches to appear. But vitiligo isn't just about what you see on the skin. It can affect how you feel about yourself, interact with others, and go about your daily life. While treatments are available, results are often not as noticeable or long-lasting as people hope.

What is Vitiligo?

Vitiligo is a chronic, autoimmune condition that presents as depigmented macules and patches, resulting from the loss of functional melanocytes. Although vitiligo is an autoimmune condition, it is frequently mischaracterized as a cosmetic or trivial condition. Those affected often experience significant quality-of-life challenges including depression and anxiety, social isolation, and work absence.

Table of Contents

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About this Study

This is a multicenter, randomized, double-blind, placebo-controlled study to investigate the safety and efficacy of an investigational treatment in participants with non-segmental vitiligo. The product is an investigational monoclonal antibody that binds to and inhibits IL-15. IL-15 is implicated in vitiligo pathogenesis through the activation and persistence of autoreactive CD8+ T cells and the maintenance of tissue-resident memory T cells (TRMs) in lesions and perilesional skin. In this study, we’re hoping to find a safe and effective dose of the investigational medicine.

We’re conducting a vitiligo research study to see if an investigational medicine could help restore the skin’s natural color for people living with vitiligo. Current treatment options are limited; there are currently no systemic medications that repigment affected areas, and many people do not see meaningful improvements with current treatments. Therefore, there remains a high clinical need for more effective and safer treatments.

What This Means for You

This vitiligo research study is researching a potential new treatment for adults living with vitiligo, a condition where the skin loses its natural color in patches. Vitiligo can affect different areas of the body and may impact confidence and quality of life.

Researchers are studying an investigational treatment designed to help restore skin pigmentation. The treatment is still being evaluated to understand how well it works and how safe it is for people with vitiligo.

Some participants in this study may receive a placebo, which looks like the study treatment but does not contain active medicine. This helps researchers compare results and better understand the effectiveness of the treatment.

The goal of this study is to learn whether this new treatment can safely improve skin repigmentation in people with non-segmental vitiligo over time.

The study team or your study doctor will explain what this means for you in detail.

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Who Can Join

The sponsor is looking for around 210 people to join this vitiligo research study. 

You may be able to participate if you:

  • Are 18 years of age or older
  • Have been diagnosed with non-segmental vitiligo
  • Have vitiligo affecting more than 5% of your body surface area
  • Have tried at least one topical (skin-applied) treatment in the past 3 months without success, or have been told by their doctor that there is no suitable topical medication

You may not be eligible if you:

  • Have previously used certain advanced or biologic treatments for vitiligo
  • Have not responded to certain systemic (whole-body) treatments in the past
  • Have undergone surgical treatments or depigmentation procedures for vitiligo
  • Are currently taking medications that may interfere with the study (the study team will review this with you)
  • Have segmental or mixed vitiligo, or other skin conditions

Not sure if you qualify?
A member of our study team will review your medical history and medications with you to determine if this vitiligo research study may be a good fit for you.

You may also qualify for other studies.

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What to Expect

Here’s what to expect if you join this vitiligo research study:

  • Study Duration: Up to 1 year and 4 months or up to 112 weeks with the optional extension period included 

  • Study Visits: During this time, you’ll have up to 31-48 clinic visits. Most visits will take approximately 2 hours.

  • Investigational Medicine: You’ll be assigned to receive either the investigational medicine or a placebo. Neither you nor the study team will know which one you’re being given.

  • Administration: You’ll receive your assigned study medicine as subcutaneous (under the skin) injections. Each dose is given as two injections. You’ll receive one dose every week for 3 weeks, and then every 2 weeks after that.

  • Optional Extension: Participants who complete the core period will be given the option to join the extension period for an additional 1 year. All participants who join the extension period will be given the investigational medicine.

  • Compensation: You may be paid (reimbursed) for reasonable time and travel costs.

If you have any other questions about what to expect from this vitiligo research study, feel free to ask the study team or your study doctor.

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See if You Qualify.

To see if you qualify or to learn more, please complete the form

Frequently Asked Questions.

What is a Clinical Trial?

A clinical trial is a research study that evaluates new medications, devices, or treatment approaches to determine if they are safe and effective. Clinical trials help doctors and researchers develop better treatments for current and future patients. All studies follow strict safety guidelines and are carefully monitored.
Each clinical study has requirements for participants based on specific factors such as age, medical history and current health. The eligibility criteria in each study protocol are used to identify the volunteers best qualified to participate.
No. Study-related medications, tests, and medical visits are provided at no cost to you. Participation in a clinical trial should not require you to pay for study-related care.
Many studies provide compensation for time and travel. Compensation varies by study and will be explained before you decide to participate.
Health insurance is not required for most clinical trials. Study-related care is typically provided at no cost to you.
Participation is completely voluntary. You may choose to leave the study at any time, for any reason. Your decision will not affect your regular medical care or benefits.
Each study has specific eligibility criteria based on age, medical history, and other factors. The best way to find out if you qualify is to complete the eligibility form or speak with a research team member.
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