Overview
Join a (MASH/NASH) Fatty Liver Disease Research Study
This study is researching potential new treatments for fatty liver disease, also known as metabolic dysfunction-associated steatohepatitis (MASH). This condition occurs when fat builds up in the liver and may lead to inflammation and liver damage over time. It is often linked to conditions like high blood pressure, diabetes, or weight-related health concerns.
Researchers are evaluating two investigational treatments, both individually and in combination, to see how they may help improve liver health. These treatments are designed to target how the body processes fat and inflammation.
Participants in this study will receive an active study treatment. There is no placebo group, and researchers will compare how different treatment approaches work.
The goal of this study is to determine whether these treatments are safe and effective in improving liver health and reducing the impact of fatty liver disease.
About the Study
We are inviting volunteers to take part in a research study testing a new potential treatment that may help manage or improve Metabolic Dysfunction-Associated Steatohepatitis (MASH).
Who Can Join
Who Can Join
- Age 18 or older
- Has fatty liver disease (specifically Metabolic dysfunction-associated steatohepatitis), which a doctor will confirm with tests like a biopsy or FibroScan
- Generally stable (good kidney function, some blood tests like liver enzymes are only slightly high)
- BMI is between 25 and 50
Who Cannot Join
You cannot join if you have any of the following:
- Other liver diseases, such as:
- Cirrhosis, liver failure, liver cancer, hepatitis, or a liver transplant
- Heart or blood issues, such as:
- High blood pressure, too high a dose of cholesterol medication (statins), uncontrolled arrhythmia, stroke, heart attack, severe heart failure, or heart surgery in the last 6 months
- Diabetes:
- Type 1 diabetes or severe type 2 diabetes
- Other serious illnesses, such as:
- Autoimmune disease, severe mental illness, or an unstable thyroid/adrenal gland problem
Not sure if you qualify? That’s okay.
A member of our recruitment team will review your medical history and medications with you to see if this study may be right for you.
What to Expect
Study Duration
Approximately 20 weeks
Study Visits
About 7 visits throughout the study
Compensation
- Participants may receive compensation up to $720 for completed study visits.
- Additional reimbursement may be provided for travel expenses with receipts.
Procedures During the Study
- Receive one of the study treatments
- Regular monitoring of liver health and overall wellness
- Blood tests and routine health assessments
- Review of medications and lifestyle factors
- Ongoing support and guidance from the study team
